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overview

I am a postdoctoral researcher in the Department of Plant Sciences at the University of California, Davis, working in the Monroe Lab, where I recently completed my Ph.D. in Plant Biology. My research sits at the intersection of evolutionary genomics, plant biology, and computational biology.

My Ph.D. work focused on understanding the evolutionary and functional consequences of loss-of-function (LoF) genetic variation in plants. I developed computational pipelines to identify LoF alleles and used genome-wide association approaches to link them to trait variation and adaptation.

I applied these methods across diverse plant systems — from the model organism Arabidopsis thaliana to economically important crops like cassava and diploid wheat — to uncover the genetic basis of adaptation, domestication, and trait diversity.

As a postdoc, I am studying somatic mutations in cassava clones, using high-quality HiFi genome assemblies of clonal accessions from various countries to date the historical spread of these clones.

education

2021 – 2026

Ph.D. in Plant Biology

University of California, Davis
Advisor: Dr. J. Grey Monroe
Dissertation: From Model to Crop: Leveraging Natural Loss-of-Function Variation and Genome-Wide Burden Tests to Understand Gene Dispensability and Accelerate Plant Breeding

2015 – 2019

B.S. in Plant Science and Technology

School of Agriculture and Biology, Shanghai Jiao Tong University
Advisor: Dr. Jingjin Zhang
Thesis: Effects of Red Light and Far-Red Light on the Growth, Development, and Hormone Levels of Water Spinach Sprouts

2017 – 2019

B.A. in English (Translation)

School of Foreign Language, Shanghai Jiao Tong University

research

2026 – presentpostdoc, Monroe Lab

Somatic Mutations in Cassava Clones

Building high-quality HiFi genome assemblies and a somatic-mutation pipeline for clonal cassava accessions from various countries, to date the historical spread of the clones.

genome assemblysomatic mutations
2021 – 2026ph.d., Monroe Lab

Loss-of-Function Burden Tests in Arabidopsis

Developing novel computational pipelines to call LoF alleles and discover causal relationships with trait variation. Computationally recapitulating flowering time networks in Arabidopsis and validating findings through RNAseq experiments.

computational genomicsGWAS
2021 – 2026ph.d., Monroe Lab

Genetic Diversity in Colombian Cassava Landraces

Analyzing over 1,000 cassava genomes, including 387 newly sequenced Colombian landraces, to investigate population structure, climate-associated genetic differentiation, and the functional consequences of LoF mutations.

population genomicsclimate adaptation
2021 – 2026ph.d., Monroe Lab

Gene Loss-of-Function in Diploid Wheat

Investigating patterns of LoF variation in Triticum monococcum and their potential roles in adaptation and domestication, bridging evolutionary biology and crop improvement.

evolutionary genomicscrop improvement
2019 – 2021master's, Maloof Lab

CRISPR Functional Analysis in Ceratopteris richardii

Developed a CRISPR/Cas9 system for C. richardii to generate knockout lines targeting CrLFY, enabling functional characterization of the LEAFY transcription factor in ferns.

CRISPR/Cas9functional genomics

publications

2025preprint

Delineating mutation bias and selection during plant development

Monroe JG, Lensink M, Ahn V, Davis M, Oya S, and Zhao K.

bioRxiv. 2025.

2026

Unlocking genetic diversity in Colombian cassava landraces for accelerated breeding

Zhao K, Long E, Sanchez F, Monier E, Chavarriaga P, and Monroe JG.

New Phytologist. 2026.

2026

Functional insights into dispensable genes using genome-wide loss-of-function burden tests in Arabidopsis

Zhao K, Lensink M, and Monroe JG.

Plant Cell. 38(4), 2026.

2025

Convergent evolution of epigenome recruited DNA repair across the Tree of Life

Monroe JG, Lee C, Quiroz D, Lensink M, Oya S, Davis M, Long E, Bird KA, Pierce A, Zhao K, et al.

eLife. 2025.

2024

H3K4me1 recruits DNA repair proteins in plants

Quiroz D, Oya S, Lopez-Mateos D, Zhao K, Pierce A, Ortega L, Ali A, Carbonell-Bejerano P, Yarov-Yarovoy V, Suzuki S, et al.

Plant Cell. 36(6):2410–2426, 2024.

2019

Growth response of water spinach sprouts to LED light intensity and light quality

Zhao S, Zhao K, Chen Z, Zhang J, Huang D.

China Vegetables. 1(6):51–57, 2019. (In Chinese)

presentations

2026

Functional insights into dispensable genes using loss-of-function burden tests in Arabidopsis

Bay Area Plant Hub 2026 Symposium, Berkeley, CA oral

2026

Functional insights into dispensable genes using loss-of-function burden tests in Arabidopsis

PAG 33 (Plant and Animal Genome Conference 33), San Diego, CA oral

2025

Functional GWAS for breeding: harnessing loss-of-function variation to fast-track gene discovery

UCD Plant Breeding Annual Retreat, Bodega Bay, CA oral

2025

Functional insights into dispensable genes using loss-of-function GWAS in Arabidopsis

PAG 32 (Plant and Animal Genome Conference 32), San Diego, CA poster

2024

Climate adaptation in cassava landraces

PAG 31 (Plant and Animal Genome Conference 31), San Diego, CA oral

2024

Utilizing loss-of-function (LoF) variations for gene discovery and crop improvement

2024 UCD PBGG Colloquium, Davis, CA oral

2022

A novel gene discovery approach: LoF-expression genome-wide association study

UCD Plant Sciences Symposium, Davis, CA poster

2021

The evolutionary significance of loss-of-function alleles in Arabidopsis thaliana transcription factors

Evolution Conference video flash talk

contact

I am always happy to discuss research collaborations, questions about my work, or opportunities in plant genomics and evolutionary biology. Feel free to reach out by email.

email
kehzhao@ucdavis.edu
address
150 California Ave, Davis, CA 95616
Department of Plant Sciences, UC Davis
scholar
Google Scholar
orcid
0009-0004-1431-637X
cv
Download full CV (PDF)